I use them, and have for a few years. For me the jury is still out.

Pros: Lighter, much lighter. Makes my steering feel lighter.

Smaller, which is great in a saddle bag.

Cons: I have several that developed pinhole leaks at higher pressure. They don’t leak fast enough to affect a ride, but the next day, they’ll definitely be down a good bit. I don’t know why this bugs me, but it does (I think I get nervous about trusting it). But I have some that are in my previous bike that are holding air fine for weeks, so it’s not an age thing. Or even a brand thing. Just seems to be luck of the draw.

Patching them - I haven’t tried often, but I haven’t had it work, even with the included patches some come with.

Cost, obviously. I got lucky and scored some on Amazon haul, getting 6 for like $8, with shipping. Extremely long stems, too, though I don’t have deep wheels. But the usual cost is much higher.

I keep buying them because I don’t want to go back, but I’m not 100% sold that the cost is worth it, either.